Neuroanesthesia and Pain Management in Small Animal Spinal Surgery

Document Type : Review article

Author
Department of Surgery and Radiology, Faculty of .Veterinary Medicine, University of Tehran, Tehran, Iran. Institute of Biomedical Research, University of Tehran, Tehran, Iran.
Abstract
Background: One of the most important and challenging aspects of neuroanesthesia in veterinary medicine is the management of anesthesia and pain in animals undergoing spinal surgery. Despite advancements in surgical techniques, pharmacological options, and physiological monitoring approaches, many patients are still at risk of associated complications.
Objectives: This review outlines key considerations related to anesthesia and analgesia in animals undergoing spinal surgery.
Methods: A review of the literature on anesthesia and analgesia management in neurosurgical procedures.
Results: Neuroanesthesia in veterinary medicine—particularly in small animals—plays a vital role in ensuring safety, minimizing complications, and promoting successful postoperative functional outcomes. The main goals of anesthesia in this field include preserving neurological function, maintaining stable blood pressure, ensuring adequate oxygenation, and preventing secondary injuries. Key principles of effective anesthetic management include the appropriate selection of anesthetic and analgesic agents, a thorough understanding of the physiology of the central and peripheral nervous systems, awareness of drug effects on spinal cord blood flow, cerebrospinal fluid (CSF) dynamics, and the blood-brain barrier (BBB), and most importantly, achieving a balance between effective sedation and analgesia while preserving neurologic function and minimizing systemic side effects.
An effective approach in this field requires a multimodal anesthesia and analgesia plan tailored to each patient's condition. The use of advanced monitoring techniques and pain management strategies—including opioids, non-steroidal anti-inflammatory drugs (NSAIDs), and regional nerve blocks—are integral components of the multimodal approach.
Conclusions: Ultimately, successful management of anesthesia and pain in spinal surgeries relies on a deep understanding of the pathophysiology of the nervous system and continuous collaboration between the anesthesia, surgical, and postoperative care teams. This coordinated approach helps prevent the exacerbation of neurological dysfunction throughout all stages of treatment and facilitates the recovery process.

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1.       Lamont L, Grimm K, Robertson S, Love L, Schroeder C, editors. Veterinary Anesthesia and Analgesia: the 6th edition of Lumb and Jones. Hoboken (NJ): John Wiley & Sons; 2024 Sep 11.
2.       Shelby AM, McKune CM. Small animal anesthesia techniques. 2nd ed. Hoboken (NJ): Wiley-Blackwell; 2022 Nov 22.
3.       Sharp NJ, Wheeler SJ. Small animal spinal disorders: diagnosis and surgery, 2nd ed. St. Louis (MO): Elsevier; 2005.
4.       Mathews K, Kronen PW, Lascelles D, Nolan A, Robertson S, Steagall PV, et al. Guidelines for recognition, assessment and treatment of pain. Vet Nurse. 2015 Apr 2;6(3):164-73.  https://doi.org/10.1111/jsap.12200.
5.       Yoo JS, Ahn J, Buvanendran A, Singh K. Multimodal analgesia in pain management after spine surgery. J Spine Surg. 2019 Sep;5(Suppl 2):S154-S60. http://dx.doi.org/10.21037/jss.2019.05.04.
6.       Woolf CJ. What is this thing called pain? J Clin Invest. 2010 Nov 1;120(11):3742-4. https://doi.org/10.1172/JCI45178.
7.       Kraus, BLH. Neuroanesthesia and pain management in spinal surgical patients [Class handout]. Ames (IA): Iowa State University, College of Veterinary Medicine; 2014 Feb.
8.       Lamont LA. Adjunctive analgesic therapy in veterinary medicine. Vet Clin North Am Small Anim Pract. 2008 Nov 1;38(6):1187-203. https://doi.org/10.1016/j.cvsm.2008.06.002.
9.       Carter AM, Yost S, Tobin J, Phuyal S, Lucke-Wold B. Pain management for the neurosurgical patient in spinal procedures: overview of historic and new modalities. Explor Drug Sci. 2024 May 21;2(3):268-76.  https://doi.org/10.37349/eds.2024.00046
10.   Hu Y, Zhou H, Zhang H, Sui Y, Zhang Z, Zou Y, et al. The neuroprotective effect of dexmedetomidine and its mechanism. Front Pharmacol. 2022 Sep 20;13:965661. https://doi.org/10.3389/fphar.2022.965661.

  • Receive Date 09 August 2025
  • Accept Date 04 October 2025
  • Publish Date 22 November 2025