List of Articles Saeed Farzad-Mohajeri

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  1 - Pathophysiology of wound healing
  Hossein Gholami Behran Zamani Rad Saeed Farzad-Mohajeri
  Wound healing is an important concern in clinical medicine. Wound healing including skin wounds is a dynamic complicated procedure which involves many different molecular and cellular agents that occur after a tissue lesion in order to repair the injured tissue. Poor wo More

  Wound healing is an important concern in clinical medicine. Wound healing including skin wounds is a dynamic complicated procedure which involves many different molecular and cellular agents that occur after a tissue lesion in order to repair the injured tissue. Poor wound healing after trauma, surgery, or chronic disease such as diabetes affects human and animal life. Well understanding this process is necessary for developing therapeutic strategies and wound management to help treatment of normal healing procedure. The repair of wounded skin is included hemostasis and inflammation, proliferation, and maturation and remodeling. These steps have considerable overlaps with each other. Manuscript profile
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  2 - Application of stem cells and tissue engineering in wound management
  Saeed Farzad-Mohajeri Mahdi ghamsari
  Optimum healing of a cutaneous wound involves a cascade of biologic cellular and molecular processes. When the normal biological process fails for any reason, healing process can cease resulting in chronic wounds. In Addition, the body cannot repair some extensive wou More

  Optimum healing of a cutaneous wound involves a cascade of biologic cellular and molecular processes. When the normal biological process fails for any reason, healing process can cease resulting in chronic wounds. In Addition, the body cannot repair some extensive wounds without problem. These Issues surrounding wound healing as well as increased medical healthcare in this field, developed novel wound therapies. Regardless of the type of these specific advanced wound care methods, the ideal goal would be to regenerate tissues such that both the structural and functional properties of the wounded tissue are restored to the levels before injury. Tissue engineering and stem cells may be the solution. A range of cell based therapies and tissue engineered scaffolds have begun to cross the rift from bench to bedside. These therapies have been heralded as a promising means by which to surpass current limitations in wound management. The wide differentiation potential of stem cells allows for the possibility of regenerating lost or damaged skin, while their ability to immunomodulate the wound bed from afar suggests that their clinical applications need not be restricted to direct tissue formation. The data suggests that the appropriate application of stem cells and scaffolds can accelerate wound healing. The clinical utility of stem cells and tissue engineering has been demonstrated across dozens of clinical trials in wound therapy. Manuscript profile
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  3 - New perspectives in wound management and treatment
  Saeed Farzad-Mohajeri Mahdi ghamsari Farzad Hayati
  Wound healing has been a major medical challenge in recent decades and it increase motivation of researchers to develop various therapeutic approaches. Along with the latest developments in science and technology, diverse approaches have been created and improved. Alt More

  Wound healing has been a major medical challenge in recent decades and it increase motivation of researchers to develop various therapeutic approaches. Along with the latest developments in science and technology, diverse approaches have been created and improved. Although Traditional management, including wound dressings and skin grafts, is still commonly used in current practice but newer technologies found their roles in wound management, such as using stem cells in skin grafts or combining traditional treatments with anti-bacterial nanoparticles. Various upcoming technologies, such as nanotechnology, biotechnology, stem cell therapy and telemedicine have emerged in recent years and are being used to assist wound healing, or even to replace traditional methods. However, many of these methods still lack assessment by large-scale studies and extensive application. Also, studies should design to explore cost-effectiveness, conveniency and efficacy of them. In this review, authors focus on and summarize recent developments involving hi-tech therapeutic methods that lead to both rapid healing and better cosmetic results. Manuscript profile