The two phenomena of wound contraction and reepithelialization which occur as stages of the repair
phase in healing of the wound play an important role in closing the damaged site. Contraction is formed
by the transformation of the modified fibroblast cells called myofibroblasts, and these cells, through their
tensile properties, pierce the wound's environment and cut the edges together, and after contacting the
two healthy regions, this process stops. Epithelialization also covers the damaged area by migrating
epithelial cells at the wound surface. These cells, by secretion of the enzymes, open their path of
movement on the wound surface and, after reaching the same cells, stop and thus the location of the
ulcer is covered and problems such as fluid loss and the entry of microbial objects to the body will be
disappeared.
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